The Start Museum is located at 111 Ruining Road, Shanghai, adjacent to the west coast of Huangpu River, and is the starting point of the Shanghai West Bund Cultural Corridor. It was founded by Mr. He Juxing and designed by Jean Nouvel, a French architect who once won the Pulitzer Prize. The building is located at the site of the Nanpu Railway Station, an early railway station in Shanghai specially for cargo transport, which is a symbolic place reminding people of the city's industrialization progress.

The Start Museum's mission is to historically unpack contemporary art, taking the objective and real history of modern art in China as the starting point for research, to unpack and discover the inseparable clues and physical evidence of international contemporary art, and to propose and study the historical perspective and values of modern art with broad value while providing experimental sites for current art production with an open stance.